Hard-to-identify E coli strain found in UK outbreak

first_img The cases in England occurred about the same time as the Scottish nursery outbreak. The English samples were received for testing between April 25 and May 4 in conjunction with cases of HUS. Typing showed the isolates to be the same, and the BBC reported that investigators from Scotland and England were working together to determine whether any common factors link the cases from the different regions. The outbreak strain grows on sorbitol-containing agar (SMAC) and does not grow on the selective media (CT-SMAC) usually used for Shiga toxin–producing E coli (STEC) O157. Thus, illness cases caused by this strain, called a sorbitol-fermenting strain, could be missed in laboratories unless other testing methods are used. Jun 8, 2006 (CIDRAP News) – An unusual strain of Escherichia coli O157 that standard laboratory culture methods cannot detect has been identified in a disease outbreak associated with a nursery in Scotland and in other cases in Scotland and England, according to recent news reports. In a BBC story, Dr Cowden said, “This unusual strain reacts differently in the laboratory from other types of E coli O157, and this is why we are interested in finding out more about it. It produces the same symptoms as other strains, and our advice to reduce the possibility of becoming infected with any type of E coli remains the same.” Four unrelated adult cases of infection with the same strain have been identified elsewhere in Scotland, as have four cases in Yorkshire and the Humber region in England, according to BBC News reports. Sorbitol-fermenting Vero cytotoxin-producing E coli O157 (VTEC O157). CDR Weekly 2006 May 25;16(21) [Full text of the issue] UK health authorities have issued revised guidelines to laboratories and specialists to address possible cases involving this strain, according to a report in the May 25 Communicable Disease Report Weekly, published by the UK Health Protection Agency. They recommend that when clinical symptoms suggest STEC, especially in children younger than 15 years and adults 65 or older, and presumptive sorbitol-nonfermenting E coli O157 colonies are not observed on SMAC or CT-SMAC, then sorbitol-fermenting colonies should be tested for agglutination with E coli O157 antiserum. Colonies that have positive agglutination tests should be identified as E coli and sent to the proper health laboratory for confirmation, phage typing, and detection of Shiga toxin genes. The disease outbreak began at a nursery in Dunfermline, Scotland, on May 9, and had involved 13 cases of gastrointestinal illness in children and adults by late May, according to BBC News reports. Four children were hospitalized for treatment for hemolytic uremic syndrome (HUS), physicians at the Royal Hospital for Sick Children in Glasgow told BBC News. Health Protection Scotland stated that the sorbitol-fermenting strain has been rare in the United Kingdom, the BBC reported. The strain had first been identified in Germany in 1988 and was thought to be restricted to continental Europe until 2002, when it was identified in Australia and the UK. See also: Dr John Cowden, a Health Protection Scotland consultant, said clinicians had been urged to ensure that this unusual strain of E coli was not missed when screening samples from patients suspected of having any type of E coli O157 infection.last_img read more

Martin Keown’s Champions League predictions, including Man Utd v Barcelona and Tottenham v Man City

first_img Liverpool v Porto Liverpool seem to save their best performances for the European stage. This victory will give them the belief they can go on to win the Premier League.Their front three – Salah, Mane and Firmino – looked hungry and back to their best. Virgil van Dijk oozed class. There was only one team in control of that match and it was Liverpool.They will be very happy at drawing Porto – a team they beat 5-0 on aggregate last season.Keown’s verdict: Liverpool Martin Keown’s Champions League predictions, including Man Utd v Barcelona and Tottenham v Man City Metro Sport ReporterSaturday 16 Mar 2019 11:28 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link776Shares The Champions League quarter-final draw has been made (Picture: Getty)The Champions League quarter-final draw was made on Friday, with Premier League champions Manchester City facing Tottenham in an all-English clash.Manchester United, who knocked PSG out of the competition, will take on European heavyweights Barcelona while Liverpool meet Porto and Ajax play Juventus.It is the first time in 48 years that England has had six quarter-finalists in major European competitions, with Chelsea and Arsenal also competing in the Europa League.Gunners hero Martin Keown expects Pep Guardiola’s Manchester City to win the Champions League and has made his quarter-final predictions in a column for the Daily Mail.ADVERTISEMENTMore: FootballRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starChelsea defender Fikayo Tomori reveals why he made U-turn over transfer deadline day moveMikel Arteta rates Thomas Partey’s chances of making his Arsenal debut vs Man City Comment Advertisement ‘You have to be disappointed’: Solskjaer reacts to 2-0 loss to ArsenalTo view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Play VideoLoaded: 0%0:00Progress: 0%PlayMuteCurrent Time 0:00/Duration Time 5:28Fullscreen’You have to be disappointed’: Solskjaer reacts to 2-0 loss to Arsenalhttps://metro.co.uk/video/you-disappointed-solskjaer-reacts-2-0-loss-arsenal-1879850/This is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. Guardiola delighted with 7-0 thrashing of SchalkeTo view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Play VideoLoaded: 0%0:00Progress: 0%PlayMuteCurrent Time 0:00/Duration Time 12:20FullscreenGuardiola delighted with 7-0 thrashing of Schalkehttps://metro.co.uk/video/guardiola-delighted-7-0-thrashing-schalke-1881604/This is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.center_img Juventus v Ajax Juventus were staring at the exit until Cristiano Ronaldo worked his magic. Success in this competition seems to drive him.Don’t count out Ajax, though. This is a magnificent young team who were better than Real Madrid over both legs.Ronaldo and Juventus to go through – but it won’t be easy.Keown’s verdict: Juventus Advertisement Manchester United v Barcelona On paper, Barcelona should be too strong for United. Lionel Messi blew them away at Wembley in the final eight years ago and his powers are not waning.But United have already won at Juventus and PSG this season. Why can’t they add Barcelona to their list of scalps?Premier League teams are strong in Europe once again and I can see United springing a surprise here.Keown’s verdict: Manchester United Klopp relishes 3-1 win to knock Bayern Munich out of Champions LeagueTo view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Play VideoLoaded: 0%0:00Progress: 0%PlayMuteCurrent Time 0:00/Duration Time 13:02FullscreenKlopp relishes 3-1 win to knock Bayern Munich out of Champions Leaguehttps://metro.co.uk/video/klopp-relishes-3-1-win-knock-bayern-munich-champions-league-1882466/This is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. Tottenham v Manchester City I’ve said that City will win the competition so I expect them to get the job done against Spurs but it won’t be easy.You only have to look at the contrasting workloads for the two teams. If Brighton win their FA Cup quarter-final on Saturday, Tottenham will have their feet up the weekend before they are due to play the first leg.City have a gruelling run of six games in just 18 days in which they will play Spurs three times, a potential FA Cup semi-final, a Manchester derby at Old Trafford and a tricky trip to Crystal Palace.Keown’s verdict: Manchester City More: FootballBruno Fernandes responds to Man Utd bust-up rumours with Ole Gunnar SolskjaerNew Manchester United signing Facundo Pellistri responds to Edinson Cavani praiseArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira moveslast_img read more